After Ramos, Varane, Mendy and Carvajal, Marcelo has also been injured.
Zinedine Zidane has only three first team defenders ready to play.
Marcelo is the last to be injured and has not been called up for the match with Granada.
In the absence of defenders, especially winged, Zizu has invited the left defender of the academy, Miguel, who played the challenge last few minutes, in the 2-2 draw with Sevilla.
Injured continue to be Dani Carvajal, Sergio Ramos, Raphael Varane, Lucas Vasquez and Ferland Mendy.
For Real it will be like a final challenge with Granada, which is still fighting for the title.
For now, La Liga depends entirely on the results of Atletico Madrid, who tonight will play the most difficult challenge of the three finals they have left – against Real Sociedad.